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KMID : 0604520060320020069
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Journal of the Society of Cosmetic Scientists of Korea
2006 Volume.32 No. 2 p.69 ~ p.74
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Effect of the Processed Selaginella tamariscina on Antioxidation and Inhibition of Matrix Metalloproteinase
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Lee Beom-Cheon
Sim Gwan-Sub
Kim Jin-Hee
Kim Jin-Hwa
Pyo Hyeong-Bae
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Abstract
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Selaginella tamariscina with the popular Korean name Keoun Back, is a traditional medicinal plant for therapy of advanced cancer patients in the Orient. In this study, we evaluated anti-aging activity of S. tamariscina using processed technology and investigated diverse biological activities of processed S. tamariscina (PST) as an anti-aging ingredient of cosmetics. PST, heated with sand, used to different purpose compared with origin in medicine. PST raises total phenol concentration and enhances the DPPH radical scavenging activity. For testing intracellular ROS scavenging activity, the cultured human dermal fibroblasts were analyzed by increase in dichlorofluorescein (DCF) fluorescence upon exposure to UVB 20 mJ/cm^2 after treatment of PST. UVA-induced MMP-1 expression in human dermal fibroblasts was reduced in a dose-dependent manner by PST. Taken together, 4hese results suggest that PST may act as an anti-aging agent by preventing the skin cell from damage induced by UV irradiation, and imply that PST may be useful as a new ingredient for anti-aging cosmetics.
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KEYWORD
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Selaginella tamariscina, anti-aging, ROS, antioxidant activity, MMP
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